- June — September
- The Professor invents the Banach-Tarski Dupla-Shrinker, and Bender accidentally creates millions of duplicates that threaten to destroy Earth (6ACV17).
- The duplicates leave Earth forever (6ACV17).
- Planet Express goes bankrupt, and the company is turned into a commercial airline. The first flight crash lands on an uncharted planet, and after finally coming home, Plan Am is closed down (6ACV20).
- The Young People's Choice Awards are held, and Turanga Leela wins for Best Children's Program for Rumbledy-hump. Later, the Cookieville Minimum-Security Orphanarium has all of its child inhabitants adopted by Abner Doubledeal to have them work on production of the rebooted reality version of the show (6ACV21).
- The common cold is reintroduced (6ACV24).