Hypermalaria
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Hypermalaria is a painful, fatal, incurable disease that is caused when exposed to methane swamps, which can either strike instantly or remain dormant for years. The symptoms are fever, spasms, madness, coma, and finally death. Professor Farnsworth once believed he had this disease, turned out to have Yetiism and was lucky enough to be cured by Dr. Zoidberg. It also causes people to rape uncontrollably.