|Planet of origin||Earth|
|Relatives||See "Family" section|
|First appearance||"Roswell that Ends Well" (3ACV19)|
|Voiced by||Tress MacNeille|
Mildred Fry worked at Joe's Malt in Roswell in 1947. She was engaged to Fry's grandfather Enos until he was killed in an atomic blast. After Enos' death she asked Fry to walk her home because he reminded her of Enos. She became attracted to Fry, not knowing that he was actually her own grandson (and Fry himself not knowing she was his grandmother), and ended up having unprotected sex with him. This resulted in Fry impregnating her and becoming his own grandfather. Amazingly, this also saved both Fry and Hubert from ceasing to exist. Also, it resulted in Fry's father becoming inbred. While she never officially married Enos, her descendants believed him to be her son's father and even named the child after her would-be father-in-law. Whether she actually took the name "Fry" is unclear.
- Yancy Fry, father-in-law
- Yancy Fry Sr., son
- Mrs. Fry, daughter-in-law
- Yancy Fry Jr., grandson
- Philip J. Fry, grandson
- Philip J. Fry, II, great-grandson
- Professor Hubert J. Farnsworth, distant grandson/descendant
- Cubert Farnsworth, Hubert Farnsworth's clone
- Turanga Leela, granddaughter-in-law
Fry: You know what really cheers you up, baking a tray of sugar cookies.
[Mildred opens her top and thrusts her breasts to seduce Fry.]
Mildred: How about these cookies, sugar?